A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top ...
Researchers at the Biocatalysis group led by Dr Francesco Mutti at the Van ‘t Hoff Institute for Molecular Sciences (University of Amsterdam) have developed a novel use of alcohol dehydrogenase (ADH) ...
A new reaction that uses an atypical starting material to create amide linkages could make it easier to prepare peptides and other amide-containing compounds that have been difficult to make until now ...
Commercial-scale amide formation and an improved process route for a tetracycline derivative are some recent developments in API synthesis. Process chemists in the fine-chemicals and pharmaceutical ...
Novel, atom-efficient routes to amides from esters and carboxylic acids for more sustainable manufacturing. It is well known that amide-formation chemistry can be inefficient and warrants further ...