Subjects came from the slow adverse vascular effects of excess weight study (SAVE), a randomized-controlled trial (NCT00366990) evaluating the effects of weight loss, increased physical activity and ...

A drug that has been used to slow progression of kidney and cardiovascular disease in people with type 2 diabetes may also help people with chronic kidney disease who do not have diabetes, according ...

Higher serum aldosterone levels among patients with chronic kidney disease (CKD) are independently associated with an increased risk for CKD progression and end-stage kidney disease (ESKD) regardless ...

A steroid hormone called aldosterone is linked to an increased risk of kidney failure in patients with chronic kidney disease (CKD), according to a study published in the European Heart Journal today ...

HYPOKALEMIC alkalosis has been variously reported as common 2,3 and rare 4 in Cushing's syndrome. Plotz, Knowlton and Ragan 5 reported 4 cases of severe hypokalemia in 31 patients with this disease.

Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

The plasma potassium level is normally maintained within narrow limits (typically, 3.5 to 5.0 mmol per liter) by multiple mechanisms that collectively make up potassium homeostasis. Such strict ...

MADRID, Spain—Baxdrostat (AstraZeneca), an investigational aldosterone synthase inhibitor, provides substantial reductions in blood pressure when added to background therapy in patients with ...