Actin is a highly abundant protein that controls the shape and movement of all our cells. Actin achieves this by assembling into filaments, one actin molecule at a time. The proteins of the formin ...

Researchers at Kanazawa University have published an article in eLife deciphering the actin structure-dependent preferential cooperative binding of cofilin. The actin filament is a double-stranded ...

Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin. The actin filament is a double-stranded helical structure ...

An electron microscopy study revealed key details of actin filaments, which are essential structural elements of cells and muscles. Actin filaments -- protein structures critical to living movement ...

Actin filaments are protein fibers that make up the internal skeleton of the cell. As active elements of our cells, actin filaments support the cell's fusion, movement and are involved in many other ...

Every time a white blood cell engulfs a bacterium, a neuron extends a projection to connect with a neighboring cell, or when a cancer cell forcefully squeezes through tissue to spread, the cell must ...

Actin filaments - protein structures critical to living movement from single cells to animals - have long been known to have polarity associated with their physical characteristics, with growing ...

Cells can spontaneously change shape even without external signals, but the underlying mechanisms behind this form of self-organization have remained unclear. Now, researchers from Japan have ...

Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...

Formins are made of two identical parts (red, orange) that encircle the actin (grey) filament in a ring-like conformation. “Our discovery allows us to interpret decades of biochemical studies on ...