McCaffrey is not in line to play in Saturday's preseason opener against the Broncos, Eric Branch of the San Francisco Chronicle and David Lombardi of SFStandard.com report. With Isaac Guerendo ...

The 49ers are limiting Christian McCaffrey's training camp reps to keep the running back healthy for the season opener and ...

The 49ers likely have no intention of playing starter Christian McCaffrey in the preseason, backup Isaac Guerendo is out for ...

Christian McCaffrey, Kyren Williams, & Najee Harris have carried heavy workloads in their NFL careers. Injury concerns will raise caution in fantasy football.

All signs point to Aiyuk starting the season on the reserve/PUP list, which would sideline him for the first four weeks of ...

When the 49ers offense is healthy, it's one of the best in the NFL. Unfortunately, their offense wasn't healthy last year, and it isn't healthy now.

Christian McCaffrey credited his wife, Olivia Culpo, for taking care of their newborn daughter while he's at San Francisco ...

Mackenzie Brooks and the Inside the Lines Team break down where every NFC West team's season is most likely to end and how to ...

Evaluating the risk-factors of Christian McCaffrey and his ability to be drafted in the first round of your fantasy football ...

Two top contenders this year face off in the preseason opener, with the San Francisco 49ers hosting the Denver Broncos. However, many fans are wondering whether stars Christian McCaffrey and Bo Nix ...

San Francisco 49ers quarterback Brock Purdy is quietly having a solid training camp. On Tuesday, he completed 10 of 15 passes ...

Christian McCaffrey was the number one draft pick in fantasy football leagues in 2024, but he missed nearly the entire season.